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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC1 All Species: 17.27
Human Site: S1497 Identified Species: 34.55
UniProt: P51610 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51610 NP_005325.2 2035 208732 S1497 S T P V P G P S V P P P E E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088011 1702 173511 S1190 M A T G A P C S A G P L L G P
Dog Lupus familis XP_867443 2039 208943 S1500 S T P V P G P S V P P P E E L
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 S1506 S T P V P G P S V P P P E E L
Rat Rattus norvegicus Q5RKG2 723 79130 F211 G S P K M Y V F G G M C G A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509058 2033 207643 P1484 Q S T P T P G P S V P P S E E
Chicken Gallus gallus XP_001234928 787 86020 T275 S A G G E I S T H D G E W K C
Frog Xenopus laevis NP_001087989 2101 219049 S1539 S R Q L P G P S V P N I S S I
Zebra Danio Brachydanio rerio Q7ZUV7 1173 122182 S661 A F Q T A V V S E Q T R Q L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 V988 S I P Q S Q P V T E T N N H S
Honey Bee Apis mellifera XP_624189 1550 166762 S1038 P E D I P I D S E P P I D T Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791039 1216 126587 S704 R A V A P Q G S S P G A S G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.3 93.8 N.A. 93.7 24.2 N.A. 82.4 26.3 68.8 20.4 N.A. 33 34.2 N.A. 37
Protein Similarity: 100 N.A. 82.5 95 N.A. 95.5 30 N.A. 86 32.2 76.6 33.1 N.A. 47.5 50.2 N.A. 46.5
P-Site Identity: 100 N.A. 13.3 100 N.A. 100 6.6 N.A. 20 6.6 46.6 6.6 N.A. 20 26.6 N.A. 20
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 13.3 N.A. 26.6 20 60 26.6 N.A. 20 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 0 9 17 0 0 0 9 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 9 % C
% Asp: 0 0 9 0 0 0 9 0 0 9 0 0 9 0 0 % D
% Glu: 0 9 0 0 9 0 0 0 17 9 0 9 25 34 9 % E
% Phe: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 17 0 34 17 0 9 17 17 0 9 17 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % H
% Ile: 0 9 0 9 0 17 0 0 0 0 0 17 0 0 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 0 9 9 9 25 % L
% Met: 9 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % N
% Pro: 9 0 42 9 50 17 42 9 0 50 50 34 0 0 9 % P
% Gln: 9 0 17 9 0 17 0 0 0 9 0 0 9 0 17 % Q
% Arg: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 9 % R
% Ser: 50 17 0 0 9 0 9 67 17 0 0 0 25 9 9 % S
% Thr: 0 25 17 9 9 0 0 9 9 0 17 0 0 9 0 % T
% Val: 0 0 9 25 0 9 17 9 34 9 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _